No, I don't mean brain hemispheres. :-p
Who here has traveled to either southern or northern hemisphere for the first time and, familiar with your native hemisphere's constellations, looked up at a mostly (aside from celestial equator overlap) unfamiliar sky?
What was that like for you?
I've imagined traveling to Australia (Cairns or Perth) and looking up. And being disoriented!
Care to share your experience in this regard?